This page includes guidelines and documents to help you understand and use guidelines in clinical settings, as discussed in the Therapeutics XI/Capstone course. It is also available on the 4th year Pharmacy student guide.
Guidelines are updated frequently and some of the guidelines linked here are in the process of being updated. We will try to keep this guide updated as new guidelines are available, but you should also check the issuing organization's web sites to see if new versions are available.
Cardiology
- 2017 ACC/AHA/HFSA Focused Updated of the 2013 ACCF/AHA Guideline for the Management of Heart FailureYancy CW, Mariell J, Bozkurt B, et al. Circulation. 2017;136(6):e137-e161
- 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood CholesterolThis guideline is very lengthy. This page includes a link to the full guideline and materials to help you interpret and apply the guideline.
- 2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary SyndromesCirculation. 2014;130:e344-e426.
- 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial InfarctionCirculation. 2013;127:e362-e425.
- Antithrombotic Therapy and Prevention of Thrombosis, 9th edChest. 2012;141(supp 2). This issue includes 21 separate guidelines that discuss antithrombotic therapy in a variety of different patient groups, with different co-morbid conditions, and in specific practice settings.
- Antithrombotic Therapy for VTE DiseaseChest. 2016:149(2);315-352.
- Guidelines for the prevention of stroke in patients with stroke and transient ischemic attackKernan WN, Ovbiagele B, Black HR, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.Stroke. 2014:45(7);2160-2236.
- 2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure: An Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2016;134(13):e282-293.
- Cardiovascular Risk Assessment: A Systematic Review of GuidelinesKhanji MY, Bicalho VVS, Waardhuizen CN, Ferket BS, Petersen SE, Hunink MGM. Cardiovascular risk assessment: A systematic review of guidelines. Ann Intern Med. 2016. doi: 10.7326/M16-1110.
The articles below are not guidelines but may be useful when interpreting guidelines or considering other aspects of patient treatment.
- A Randomized Trial of Intensive versus Standard Blood-Pressure ControlSPRINT Research Group. A randomized trial of intensive versus standard blood-pressure control. New Engl J Med. 2015:373(22);2103-2116.
- Angiotensin-Neprilysin Inhibition versus Enalapril in Heart FailureMcMurray JJV, Packer M, Desai AS, et al. Angiotension-neprilysin inhibition versus Enalapril in heart failure. New Engl J Med. 2014:371(11);993-1004.
Cardiology Articles for APPE
COPD
The following item is not a guideline, but a foundational article relating to the guidelines above.
Diabetes
- Summary of revisions: Standards of Medical Care in Diabetes- 2018. Diabetes Care.2018;41(Suppl 1): S4-S6.This summary of the changes to the new guidelines is a good option for a quick read.
- Standards of medical care in diabetes- 2018. Diabetes Care. 2018;41(Suppl 1):S1-S159.This is an entire issue of a journal, consisting of short guidelines focused on specific populations.
Dyslipidemia
- 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood CholesterolThis guideline is very lengthy. This page includes a link to the full guideline and materials to help you interpret and apply the guideline.
These materials refer to the 2014 guidelines, which have been replaced by the 2018 guidelines.
Gastroenterology
- Update on Prevention, Diagnosis, and Treatment of Chronic Hepatitis B: AASLD 2018 Hepatitis B GuidanceTerrault NA, Lok ASF, McMahon BJ, et al. Hepatology. 2018;67(4):1560-1599
- Hepatitis C Guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis c virus.Hepatology. 2015;(62(3):932-954.
Hematology/Oncology
The National Comprehensive Cancer Network (NCCN) is a major creator and provider of evidence-based guidelines. Visit the NCCN Guidelines page to access individual guidelines covering treatment; detection, prevention, and risk reduction; supportive care; age-related recommendations; and guidelines in patient-friendly language.
Hypertension
Infectious Disease
Many guidelines linked here from the Infectious Diseases Society of America are being updated. We will try to keep this guide updated as new guidelines are available, but you should also check the IDSA guidelines site to see if new versions are available.
- Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of AmericaCln Infect Dis. 2016;63(4):e1-e60
- Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of AmericaClin Infect Dis. 2016;62(4):e1-e50
- Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016.Crit Care Med. 2017;45(3):486-552
- Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious DiseasesRybak M, Lomaestro B, Rotschafer JC, et al.. Am J Health Sys Pharm. 2009:66 (1);82.
- International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in womenEuropean Society for Microbiology and Infectious Diseases.Clin Infect Dis. 2011:52(5);e103.
- CDC Influenza.Click "health professionals" to see recommendations for clinicians. Other portions of this site have useful information for patient counseling.
Neurology
- Practice Guideline update summary: Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsyKanner AM, Ashman E, Gloss D, et al. Report of the American Epilepsy Society and the Guideline development, dissemination, and Implementation subcommittee of the American American Academy of Neurology. Epilepsy Curr. 2018;18(4):260-268.
- Evidence-based guideline: intravenous immunoglobulin in the treatment of neuromuscular disordersPatwa HS, Chaudhry V, Katzberg H, Rae-Grant AD, So YT. Evidence-based guideline: intravenous immunoglobulin in the treatment of neuromuscular disorders: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2012:78(13);1009-1015.
- Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs II: Treatment-resistant epilepsyKanner AM, Ashman E, Gloss D, et al. Report of the American Epilepsy Society and the Guideline development, dissemination, and Implementation subcommittee of the American American Academy of Neurology. Epilepsy Curr. 2018:18(4):269-278.
- Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults.Silberstein SD, Holland S, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2012:78(17);1337-1345.
Psychiatry
- APA GuidelinesThe American Psychiatric Association (APA) is a major producer of practice guidelines providing evidence-based recommendations for the assessment and treatment of psychiatric disorders. View the APA's Guidelines page for additional guidelines in psychiatric care.
- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorderYatham LN, Kennedy SH, Parikh SV, et al. Bipolar Disord. 2018;20(2):97-170.
- Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Clinical Practice Guideline for the Pharmacological Treatment of chronic insomnia in adults: an American Academy of Sleep Medicine Clinical Practice GuidelineJournal of Clinical Sleep Medicine. 2017. 13(2):307-349.
Toxicology
Guidelines
- ECRI Guidelines Trust This link opens in a new windowFind summaries of high-quality guidelines from state, federal, and international agencies. Requires free registration. Similar to National Guideline Clearinghouse.
- CINAHL Complete This link opens in a new windowPrior to searching, use the Publication Type limit of Practice Guidelines.
- Guidelines.co.uk This link opens in a new windowSummaries of guidelines and recommendations from United Kingdom governmental agencies and European and global professional groups. Includes links to full-text of guidelines. Registration is not required to access guidelines.
- National Institute for Health and Clinical Excellence (NICE) This link opens in a new windowGuidelines for United Kingdom (UK) National Health Services (NHS).
Professional groups, non-profit organizations, and government agencies often develop guidelines and make them available freely on their websites. Search or browse groups like the World Health Organization, U.S. Centers for Disease Control and Prevention, U.S. Veterans Health Administration, or U.S. Preventive Services Task Force. Use Google to find additional groups focused on your specialty.
National Guideline Clearinghouse ceased in July 2018. There is no replacement product with the scope and depth of NGC. Use one or more of these sources to identify and access full-text guidelines.