Bioinformatics Software: Ingenuity Pathway Analysis (IPA)

Ingenuity Pathway Analysis (IPA) is a web-based functional analysis tool for omics data.

Make Sense of Your Omics Data

• Identify the most relevant signaling and metabolic pathways, molecular networks, and biological functions for list of genes
• Predict the direction of downstream effects on biological and disease processes
• Predict the activation and inhibition of upstream transcription factors
• Compare affected pathways and phenotypes across multiple testing conditions

Search and Explore Biological and Chemical Knowledge

• Quickly gain knowledge on genes and chemicals by browsing categorized and curated publications
• Dynamically build and explore bio-molecule interaction networks supported by literature findings
• Identify potential biological impacts of custom networks
• Generate testable hypothesis for your genes of interest

IPA is one of the best functional analysis and knowledge discovery tool.  It is widely used by the life science community. 

• Up-to-date high quality knowledgebase manually curated by PhD scientists
• Search for targeted information on genes, proteins, chemicals, and drugs
• Extensive library of well-characterized signaling and metabolic pathways offer a starting point for exploration and a bridge between novel discovery and known biology. Layer in novel insights, drugs, and 'omics data.
• Extensive knowledge database on model organisms human, mouse, rat. Additional species supported via ortholog mapping.
• Easy and flexible collaboration and results sharing.

Chargeback fees apply for the use of IPA through the USC license. 

To get a USC IPA account:

1. Carefully review the Bioinformatics Software Chargeback Policy (pricing, billing, usage notes and tips) and the IPA user policy
2. Fill out and submit the IPA Registration Form.  IPA login is integrated with USC's Single Sign-on protocol (SSO), as such, you must provide your primary USC email address on the registration form.
3. Activate your account following the link in the confirmation email from Qiagen (may take 1-2 business days)

To log in USC IPA:

1. Download and install the latest IPA launcher: https://analysis.ingenuity.com/pa/installer/select
2. Click on the IPA launcher icon, enter your USC primary email address and a USC-SSO login window will pop-up
3. Complete the USC-SSO login and you will be automatically logged into IPA.  
4. If you encounter any login-related error messages in your web browser, please clear the cache of your default web browser and then click on the IPA launcher icon to restart the login process.

Get started with video tutorials

• New user training
• Data type specific training
• Information for intermediate user

Help @ Ingenuity Systems

• Check out the online help page for a wealth of useful information, including case studies, white papers and FAQs
• Contact Ingenuity support
  • by phone: 866.464.3684 (6am - 5pm PST)
  • by email: ts-bioinformatics@qiagen.com
• Additional resources including webinar archives

Help @ USC Libraries Bioinformatics Service

• Email us: nmlbio@usc.edu​